• Multiple Chemical Sensitivity: Catching up to what kind of science? 

      Pitron, Victor; Köteles, Ferenc Gabor; Nordin, Steven; Haanes, Jan Vilis; Hillert, Lena; Léger, Damien; Lemogne, Cédric; Szemerszky, Renata; van Kamp, Irene; van Thriel, Christoph; Witthöft, Michael; Van den Bergh, Omer (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-12-27)
      The recent review of Molot et al. (2023) appropriately emphasizes Multiple Chemical Sensitivity (MCS) as a growing health issue and the necessity of dedicated healthcare and medical education. The authors explain MCS mainly as the result of the sensitization of transient receptor potential (TRP) receptors, notably TRPV1 and TRPA1, and oppose this explanation to psychological processes as a causal ...
    • Prediction of human drug-induced liver injury (DILI) in relation to oral doses and blood concentrations 

      Albrecht, Wiebke; Kappenberg, Franziska; Brecklinghaus, Tim; Stoeber, Regina; Marchan, Rosemarie; Zhang, Mian; Ebbert, Kristina; Kirschner, Hendrik; Grinberg, Marianna; Leist, Marcel; Moritz, Wolfgang; Cadenas, Cristina; Ghallab, Ahmed; Reinders, Jörg; Vartak, Nachiket; van Thriel, Christoph; Golka, Klaus; Tolosa, Laia; Castell, José V.; Damm, Georg; Seehofer, Daniel; Lampen, Alfonso; Braeuning, Albert; Buhrke, Thorsten; Behr, Anne-Cathrin; Oberemm, Axel; Gu, Xiaolong; Kittana, Naim; van de Water, Bob; Kreiling, Reinhard; Fayyaz, Susann; van Aerts, Leon; Smedsrød, Bård; Ellinger-Ziegelbauer, Heidrun; Steger-Hartmann, Thomas; Gundert-Remy, Ursula; Zeigerer, Anja; Ullrich, Anett; Runge, Dieter; Lee, Serene M.L.; Schiergens, Tobias S.; Kuepfer, Lars; Aguayo-Orozco, Alejandro; Sachinidis, Agapios; Edlund, Karolina; Gardner, Iain; Rahnenführer, Jörg; Hengstler, Jan G. (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-06-27)
      Drug-induced liver injury (DILI) cannot be accurately predicted by animal models. In addition, currently available in vitro methods do not allow for the estimation of hepatotoxic doses or the determination of an acceptable daily intake (ADI). To overcome this limitation, an in vitro/in silico method was established that predicts the risk of human DILI in relation to oral doses and blood concentrations. ...
    • “Symptoms associated with environmental factors” (SAEF) – Towards a paradigm shift regarding “idiopathic environmental intolerance” and related phenomena 

      Haanes, Jan Vilis; Nordin, Steven; Hillert, Lena; Witthöft, Michael; van Kamp, Irene; van Thriel, Christoph; Van den Bergh, Omer (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-02-05)
      Health conditions characterized by symptoms associated with chemical, physical and biological environmental factors unrelated to objectifiable pathophysiological mechanisms are often labelled by the general term “idiopathic environmental intolerances”. More specific, exposure-related terms are also used, e.g. “multiple chemical sensitivities”, “electromagnetic hypersensitivity” and “candidiasis ...
    • “Symptoms associated with environmental factors” (SAEF) – Towards a paradigm shift regarding “idiopathic environmental intolerance” and related phenomena 

      Haanes, Jan Vilis; Nordin, Steven; Hillert, Lena; Witthöft, Michael; van Kamp, Irene; van Thriel, Christoph; Van den Bergh, Omer (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-02-05)
      Health conditions characterized by symptoms associated with chemical, physical and biological environmental factors unrelated to objectifiable pathophysiological mechanisms are often labelled by the general term “idiopathic environmental intolerances”. More specific, exposure-related terms are also used, e.g. “multiple chemical sensitivities”, “electromagnetic hypersensitivity” and “candidiasis ...